Endocrine Abstracts

We present a 23 years old woman presenting in the 22nd week of pregnancy with 3 months history of facial hirsutism and progressive deepening of her voice. There had been an episode of vaginal bleeding during the 8th week of pregnancy. Prior to pregnancy the patient had been well and had had no symptoms suggestive of hyperandrogenism. On examination she had facial hirsutism. Her voice was deep. Florid abdominal striae were noted. Examination was otherwise unremarkable.<p cl...

Background: We have previously demonstrated that the natriuretic peptides BNP and NT-proBNP rise with ascent to high altitude (HA). Both peptides are classically markers of congestive cardiac failure but have also recently been found to be associated with pulmonary hypertension at sea-level (SL). As pulmonary hypertension is central to the risk of high altitude pulmonary oedema we aimed to establish if there was any association between high pulmonary artery systolic pressure (...